Organic thin-film transistors (OTFTs) have shown promise for a range of sensing applications, with phthalocyanine-based OTFTs demonstrated as sensors for atmospheric parameters, volatile gases, and small organic molecules including cannabinoids. However, the process of fabricating, testing, and optimizing OTFTs in a laboratory setting requires highly specialized equipment, materials, and expertise. To determine if sensor development can be expedited and thus reduce manufacturing burden, spectroelectrochemistry is applied to rapidly screen for molecular interactions between metal-free phthalocyanines and a variety of metal phthalocyanines (MPcs) and the cannabinoids Δ9-tetrahydrocannabinol (THC) or cannabidiol (CBD), with and without a cannabinoid-sensitive chromophore (Fast Blue BB). Spectral analyses are corroborated by 2D-NMR and related to measured OTFT performance. Spectroelectrochemical changes to the Q band region of the phthalocyanine spectra in the presence of analytes can be used to predict the response of OTFTs. Thus, with spectroelectrochemistry, a range of potential materials for OTFT small organic molecule-sensing applications can be quickly analyzed, and phthalocyanines with a preferred response can be selected.The increase of proton beam number might provide higher degrees of freedom in the optimization of intensity-modulated proton therapy planning. In this study, we aimed to quantitatively explore the potential benefits of the increased beam number, including dose volume histogram (DVH), linear energy transfer volume histogram, and DVH bandwidth metrics. Twelve patients with lung cancer are retrospectively selected. Four plans were created based on internal target volume (ITV) robust optimization for each patient using the RayStation treatment planning system. Selleck Colforsin Four plans were generated using different numbers (three, five, seven, and nine) of evenly separated coplanar beams. The three-beam plan was considered as the reference plan. Biologically equivalent doses were calculated using both constant relative biological effectiveness (RBE) and variable RBE models, respectively. To evaluate plan quality, DVH metrics in the target [ITV D2%, CI, HI] and organs-at-risk [Lung V5Gy[RBE], V20Gy[RBE], V30Gy[RBE]; Heart D2%; stness of cord hot spots became worse using five and seven beams compared to that using three beams. As the proton beam number increased, plan quality and LET distributions were comparable or significantly improved. The robustness of target dose coverage, target dose hot spots, and low-dose lung volume were significantly improved.An ideal oil/water separation membrane should possess the characteristics of high flux and separation efficiency, recyclability, as well as good mechanical stability. Herein, a facile method is applied to fabricate a Janus polylactic acid (PLA) fibrous membrane for efficiently separating surfactant-stabilized oil/water mixtures. The Janus PLA fibrous membrane architecture was prepared by electrospinning a PLA/carbon nanotubes (CNTs) fibrous membrane and the subsequent electrospinning of a PLA/SiO2 nanofluids (nfs) membrane onto one side of the PLA/CNTs fibrous membrane. Due to the strong electrostatic interaction between SiO2 nfs and CNTs, synchronous enhancement and plasticization of PLA fibrous membranes were achieved, which was far superior to that reported in the literature. The introduction of CNTs had caused an upshift of the hydrophobicity of the PLA/CNTs fibrous membrane (water contact angle (WCA) > 140°). In contrast, SiO2 nfs bearing long-chain organic anions and cations located onto the surface of the fibers during electrospinning to achieve superhydrophilicity (WCA ≈ 0°). Benefiting from completely opposite wettability on both sides of the Janus membrane, the obtained asymmetric Janus membranes exhibited a high flux (1142-1485 L m-2 L-1) and excellent oil/water separation efficiency (>99%), which were superior to those reported for other Janus membranes. Furthermore, the Janus membranes showed desirable flux recovery without any treatment (>80% for water-in-oil emulsions and >90% for oil-in-water emulsions, respectively, after 11 cycles), showcasing promising applications for water treatment in the future.Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years have seen the development of PPGs activatable by biologically and chemically benign visible and near-infrared (NIR) light. These long-wavelength-absorbing moieties expand the applicability of this powerful method and its accessibility to non-specialist users. This review comprehensively covers organic and transition metal-containing photoactivatable compounds (complexes) that absorb in the visible- and NIR-range to release various leaving groups and gasotransmitters (carbon monoxide, nitric oxide, and hydrogen sulfide). The text also covers visible- and NIR-light-induced photosensitized release using molecular sensitizers, quantum dots, and upconversion and second-harmonic nanoparticles, as well as release via photodynamic (photooxygenation by singlet oxygen) and photothermal effects. Release from photoactivatable polymers, micelles, vesicles, and photoswitches, along with the related emerging field of photopharmacology, is discussed at the end of the review.A single-structured multifunctional device capable of energy harvesting and sensing multiple physical signals has significant potential for a wide range of applications in the Internet of Things (IoT). In this study, the fabricated single-structured device based on methylammonium lead iodide-polyvinylidene fluoride (MAPbI3-PVDF) composite can harvest mechanical energy and simultaneously operate as a self-powered light and pressure sensor because of the combined photoelectric and piezoelectric/triboelectric properties of the MAPbI3-PVDF composite. Light-dependent dielectric and piezoelectric properties of composite films are thoroughly investigated. Light and contact electrification effect on device performance in both piezoelectric and triboelectric modes is also systematically investigated. When the device is operated as a harvester in both piezoelectric and triboelectric modes, remarkable light-driven outputs were observed under illumination; the outputs decreased in the piezoelectric mode, while they increased in the triboelectric mode.Selleck Colforsin