51, 95% confidence interval (CI) 1.40 to 1.60) and of bipolar disorder (aHR 1.14, 95% CI 1.04 to 1.24) in people with prior-recorded MS and of subsequent MS in people with prior-recorded schizophrenia (aHR 1.26, 1.15-1.37) or bipolar disorder (aHR 1.73, 1.57-1.91), but most of these associations were reduced to null when analyses were confined to diagnoses recorded as the primary reason for admission.

Further research is needed to investigate the potential association between MS and schizophrenia and/or bipolar disorder as it may shed light on underlying pathophysiology and help identify potential shared risk factors.
Further research is needed to investigate the potential association between MS and schizophrenia and/or bipolar disorder as it may shed light on underlying pathophysiology and help identify potential shared risk factors.
Previous studies have shown that an intellectually stimulating lifestyle is associated with a lower risk for cognitive decline and Alzheimer's disease and related dementia (ADRD). It is unclear so far whether higher intelligence may protect against this. The aim of this study was to conduct a systematic review on the association between intelligence and cognitive decline and ADRD risk.

We searched the PubMed, web of science, and Scopus databases following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) and Population, Intervention, Comparison, and Outcome (PICO) criteria. Quality of evidence was assessed using Critical Appraisal Skills Programme (CASP) checklists.

From an initial n=8,371 search hits, n= 14 studies met the inclusion criteria and had sufficient quality. Evidence indicates that cognitive decline in old age is not significantly associated with childhood intelligence (n=9). Evidence with regard to ADRD risk is inconclusive (n=5) with some studies showing no effects and other studies with significant effects having limitations in their design.

Even though the majority of the studies show no significant association, we cannot exclude a possible effect that might be moderated by other, so far unknown factors. Further studies are necessary to systematically assess the influence of intelligence on ADRD risk and what factors moderate this association.
Even though the majority of the studies show no significant association, we cannot exclude a possible effect that might be moderated by other, so far unknown factors. Further studies are necessary to systematically assess the influence of intelligence on ADRD risk and what factors moderate this association.Faces and voices are very important sources of threat in social anxiety disorder (SAD), a common psychiatric disorder where core elements are fears of social exclusion and negative evaluation. Previous research in social anxiety evidenced increased cerebral responses to negative facial or vocal expressions and also generally increased hemodynamic responses to voices and faces. But it is unclear if also the cerebral process of face-voice-integration is altered in SAD. Applying functional magnetic resonance imaging, we investigated the correlates of the audiovisual integration of dynamic faces and voices in SAD as compared to healthy individuals. In the bilateral midsections of the superior temporal sulcus (STS) increased integration effects in SAD were observed driven by greater activation increases during audiovisual stimulation as compared to auditory stimulation. TH-257 manufacturer This effect was accompanied by increased functional connectivity with the visual association cortex and a more anterior position of the individual integration maxima along the STS in SAD. These findings demonstrate that the audiovisual integration of facial and vocal cues in SAD is not only systematically altered with regard to intensity and connectivity but also the individual location of the integration areas within the STS. These combined findings offer a novel perspective on the neuronal representation of social signal processing in individuals suffering from SAD.
Mobile phone addiction behaviors (MPAB) are extensively associated with several mental and sleep problems. Only a limited number of bidirectional longitudinal papers have focused on this field. This study aimed to examine the bidirectional associations of MPAB with mental distress, sleep disturbances, and sleep patterns.

A total of 940 and 902 (response rate 95.9%) students participated at baseline and one-year follow-up, respectively. Self-reported severity of mobile phone addiction was measured using Mobile Phone Involvement Questionnaire (MPIQ). Mental distress was evaluated by using Beck Depression Inventory (BDI) and Zung Self-Rating Anxiety Scale (SAS). Sleep disturbances were assessed by using Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Sleep patterns were evaluated by using reduced Morningness-Eveningness Questionnaire (rMEQ), weekday sleep duration, and weekend sleep duration.

Cross-lagged analyses revealed a higher total score of BDI, SAS, and ISI predicted a greater likelihood of subsequent MPAB, but not vice versa. We found the bidirectional longitudinal relationships between MPAB and the total score of PSQI and ESS. Besides, a higher score of MPIQ at baseline predicts a subsequent lower total score of rMEQ and shorter weekday sleep duration.

The current study expands our understanding of causal relationships of MPAB with mental distress, sleep disturbances, and sleep patterns.
The current study expands our understanding of causal relationships of MPAB with mental distress, sleep disturbances, and sleep patterns.
Existing satisfaction measures cover general feelings of well-being among older adults, but it is not clear whether life satisfaction is associated with depressive symptoms that decrease psychological well-being. We developed a new life satisfaction scale to assess the associations of health, social factors, and interpersonal relationships with overall life satisfaction. The structural and predictive validity of the scale regarding the onset of depressive symptoms was examined.

A 13-item questionnaire was developed based on a literature review. The response options for all of the questions were 1 = poor, 2 = not very good, 3 = good, and 4 = excellent. For the analysis, a total satisfaction score was calculated by summing the individual scores (range = 13-52), and higher scores indicated higher overall satisfaction. Baseline data were obtained using the Geriatric Depression Scale-Short Form with a 30-month follow-up. Older Japanese adults (
= 1,792, mean age 70.1 ± 6.3 years, 46.4% male) participated in both surveys.TH-257 manufacturer