Microsoft Edge has a command palette which allows you to run commands by typing. You can use this to launch Developer Tools for Node.

• Press Ctrl+Q to open the command palette
• Type >, node and press Enter

Alternatively, you can always use the old way to access Node devtools using edge://inspect and clicking the link.

If you don't see the command palette

This is being currently rolled out in Edge, so if you don't see it yet, you need to go to edge://flags and turn it on: